Antibacterial activity of Piper betle L. (Piperaceae) and its products

Ho Thi Thach Thuy Thuy; Tran Do Cong Danh; Dang Thi Le Thuy; Ly Hong Huong Ha

doi:10.59294/HIUJS2025027

Từ khóa:

Piper betle, antibacterial, essential oil

Tóm tắt

Introduction: Piper betle L. is a common species in many countries and is used in the production of natural products mainly for its antibacterial activity. Objective: To investigate the antibacterial ability of 96%, 70%, 50% ethanol extracts, essential oils, and products from P. betle. Research methods: agar disc diffusion and dilution methods to determine MIC (minimum inhibitory concentration). Results: The extracts and essential oils of P. betle have good effects on 2 strains of bacteria E.coli and S.aureus, in which the extract with the best MIC is 96% ethanol extract (0.312 mg/mL and 0.078 mg/mL for E. coli and S. aureus, respectively). The MICs of essential oils were 0.5% and 0.0312% for E. coli and S. aureus, respectively, while products from P. betle were only active against S. aureus but had no effect on E.coli strains. Conclusion: Extracts, essential oils, and preparations from P.betle have antibacterial activity against two strains of bacteria, E.coli and S.aureus. Research should be directed to other strains of bacteria for more comprehensive evaluation.

Abstract

Introduction: Piper betle L. is a common species in many countries and is used in the production of natural products mainly for its antibacterial activity. Objective: To investigate the antibacterial ability of 96%, 70%, 50% ethanol extracts, essential oils, and products from P. betle. Research methods: agar disc diffusion and dilution methods to determine MIC (minimum inhibitory concentration). Results: The extracts and essential oils of P. betle have good effects on 2 strains of bacteria E.coli and S.aureus, in which the extract with the best MIC is 96% ethanol extract (0.312 mg/mL and 0.078 mg/mL for E. coli and S. aureus, respectively). The MICs of essential oils were 0.5% and 0.0312% for E. coli and S. aureus, respectively, while products from P. betle were only active against S. aureus but had no effect on E.coli strains. Conclusion: Extracts, essential oils, and preparations from P.betle have antibacterial activity against two strains of bacteria, E.coli and S.aureus. Research should be directed to other strains of bacteria for more comprehensive evaluation.

Tài liệu tham khảo

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