Identification of phytochemistry composition and antibacterial activity of the trunk Vernonia amygdalina

Authors

  • Thai Thi Cam Nguyen Tat Thanh University https://orcid.org/0000-0002-3752-9683
  • Nguyen Thi My Hanh Nam Can Tho University
  • Tran Duy Khang Nam Can Tho University
  • Nguyen Thi Linh Em Nam Can Tho University
  • Nguyen Duy Tuan Nam Can Tho University
  • Nguyen Thi Le Huyen Nam Can Tho University
  • Ngo Hong Phong Nam Can Tho University
  • Pham Van Vi Nam Can Tho University

DOI:

https://doi.org/10.59294/HIUJS.34.2025.748

Keywords:

Vernonia amygdalina, phytochemistry composition, antibacterial

Abstract

Background: Vernonia amygdalina origins of Africa. Today, it is widely grown in Vietnam. Vernonia amygdalina is used by people for antibacterial purposes, hypoglycemic, protecting the liver, etc. However, there is not much research data on the trunk of this tree. Objectives: Analysis of chemical composition and antibacterial effects of the trunk Vernonia amygdalina. Materials and methods: The trunk of Vernonia amygdalina was collected in Binh Thuy district, Can Tho City. Chemical composition analysis was conducted based on the improved Ciuley method. Moreover, the antibacterial activity was investigated by using the agar diffusion method. Results: The trunk of Vernonia amygdalina contains carotenoids, coumarins, triterpenoids, saponins, flavonoids, etc. Additionally, extracts from the trunk of Vernonia amygdalina have antibacterial properties against Staphylococcus aureus, Pseudomonas aeruginosa, and E. coli bacteria with an aseptic ring sizes of 7.33 mm, 2 mm, and 4.67 mm respectively at the concentration of 200 mg/mL. Conclusions: Vernonia amygdalina of trunk was collected in Can Tho City which contained various compounds including carotenoids, coumarins, triterpenoids, saponins, flavonoids, etc. Notably, 70% alcohol extract of vernonia amygdalina trunk has the highest antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and E. coli at a concentration of 200 mg/mL.

Author Biographies

Nguyen Thi My Hanh, Nam Can Tho University

Thạc sĩ chuyên ngành Dược lý - Dược lâm sàng, thuộc Bộ môn Dược lý - Dược lâm sàng, Khoa Dược - Trường ĐH Nam Cần Thơ

Tran Duy Khang, Nam Can Tho University

Thạc sĩ Hóa học, Bộ môn Hóa lý - Hóa Dược, Khoa Dược,  Trường ĐH Nam Cần Thơ

Nguyen Thi Linh Em, Nam Can Tho University

Thạc sĩ Dược lý - Dược lâm sàng, Bộ môn Dược lý - Dược lâm sàng, Khoa Dược - Trường ĐH Nam Cần Thơ

Nguyen Duy Tuan, Nam Can Tho University

Thạc sĩ Hóa học, Bộ môn Hóa hữu cơ - Trường ĐH Nam Cần Thơ

Nguyen Thi Le Huyen, Nam Can Tho University

Tiến sĩ Hóa học, Bộ môn Hóa lý - Hóa dược, Trường ĐH Nam Cần Thơ

Ngo Hong Phong, Nam Can Tho University

Thạc sĩ Kiểm nghiệm thuốc và Độc chất, Bộ môn Hóa phân tích -nKiểm nghiệm, nhphong@nctu.edu.vn

Pham Van Vi, Nam Can Tho University

Thạc sĩ Dược lý - Dược lâm sàng, Trung tâm thực hành, Trường ĐH Nam Cần Thơ

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Published

24.03.2025

How to Cite

[1]
T. T. Cam, “ Identification of phytochemistry composition and antibacterial activity of the trunk Vernonia amygdalina”, HIUJS, vol. 34, pp. 113–120, Mar. 2025.

Issue

Section

PHARMACY

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