Olean-type triterpenoid and norlignan isolated from the roots of Parietaria Debilis G. Forst., Urticaceae
DOI:
https://doi.org/10.59294/HIUJS.27.2024.574Keywords:
Sam dat Con Dao, Parietaria debilis, maslinic acid, pouzolignan NAbstract
Background: Sam dat Con Dao (Parietaria debilis G. Forst., Urticaceae) has long been used by people living in Con Dao as an herbal to improve, enhance health, and prevent diseases. In Vietnam, there are currently not many research works on Sam dat Con Dao to clarify the chemical composition of this species. Objective: This study was conducted to isolate and determine the structure of compounds in DCM extract extracted from the roots of Sam dat Con Dao. Materials and methods: The roots of Parietaria debilis G. Forst., were collected in Con Dao National Park in May 2018. Plant material was macerated with ethanol 96%. The crude extract was separated by liquid-liquid distribution. The isolations of pure compounds were carried out using column chromatography (classical column chromatography, Sephadex chromatography). The structures of isolated compounds were identified by MS and NMR methods. Results: From the DCM fraction, two compounds were isolated and identified as Maslinic acid and Pouzolignan N. Conclusion: The chemical study of DCM fraction extracted from the roots of Parietaria debilis G.Forst. led to the isolation of two compounds: Maslinic acid and Pouzolignan N. Moreover, two compounds were isolated for the first time in this species.
References
[1] N.T. Mau, L.V. Minh, H.Q. Tuan, and T.C. Luan, “Study on botanical characteristics of Parietaria debilis G. Forst., Urticaceae”, Ho Chi Minh City Journal of Medicine, Supplement of Vol. 24 - No. 3, 19 – 25, 2020.
[2] H.Q. Tuan, T.C. Luan, N.T. Mau, “Hopane-Type Triterpenoids and Sterol from the Root of Parietaria debilis Forst.F. Urticaceae”, Proceedings of international workshop 2019 on trade science – technology development in the Mekong delta in the context of international integration, 531-537, 2019.
[3] Q.T.T. Van, L.T. Vien, T.T.H. Hanh,...,C.V. Minh, “Triterpenoid derivatives from Barringtonia racemosa”. Vietnam Journal of Chemistry, 57(1), 96–100, 2019. DOI: 10.1002/vjch.201900006.
DOI: https://doi.org/10.1002/vjch.201900006[4] L. T. H. Nhung, P.T.M. Huong, N.T. Anh,..., P.V. Kiem, “Two new norlignans from the aerial parts of Pouzolzia sanguinea (Blume) Merr”, Natural Product Research, 36(1), 157–164, 2020. DOI: 10.1080/14786419.2020.1771707.
DOI: https://doi.org/10.1080/14786419.2020.1771707[5] H. K. Assaf, A.M. Nafady, M.S. Abdelkader, A.E. Allam, and M.S. Kamel, “Phytochemical and biological studies of aerial parts of Forsskaolea tenacissima Linn. (Urticaceae)”, Journal of Pharmacognosy and Phytochemistry, 4(3):282-90, 2015.
[6] Q. Xu, G. Chen, J. Fan,..., X. Li, “Chemical constituentsof roots of Boehmeria nivea”, Journal of Chinese Materia Medica, 34(20),2610-2, 2009.
[7] H. K. Assaf, A.M. Nafady, A.E. Allam, A. Hamed, and M.S. Kamel, “Phytochemistry and biological activity of family “Urticaceae”: a review (1957-2019)”, Social Science Research Network, 2021. DOI: 10.2139/ssrn.3776660.
DOI: https://doi.org/10.2139/ssrn.3776660
